One of the Largest Studies in Adults 75 Years or Older

PREVENTABLE is one of the largest research studies in older adults. The purpose is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. A statin is a commonly used drug to lower cholesterol.

Why is PREVENTABLE Important?

The benefits of taking statins for older adults without heart disease are not fully understood. Results from PREVENTABLE will help us learn if taking a statin is helpful for older adults.

Who is Involved in PREVENTABLE?

About 20,000 older adults along with a team of researchers, clinicians, participant advisors, and community partners.
The study receives funding from the National Institute on Aging (NIA) and the National Heart Lung Blood Institute (NHLBI), which are both part of the National Institutes of Health (NIH).


Researchers and doctors at 100 health systems across the United States are participating in the PREVENTABLE study.

The health systems include the Veterans Affairs and institutions that are part of PCORnet®, The National Patient-Centered Clinical Research Network.
Check the STUDY LOCATIONS menu item above to see a detailed list of health systems that are participating in PREVENTABLE. You can speak with your clinician about PREVENTABLE.

How is PREVENTABLE Different?

PREVENTABLE is considered a pragmatic study. Pragmatic studies make participating in research easy by using new methods to connect researchers with participants where they live and on their schedule. Pragmatic studies also test if a drug has the expected effects rather than how it works.

Pragmatic studies like PREVENTABLE are particularly ideal for older adults. We will follow study participants by reviewing their health records and through a phone call or a home visit. We will also mail study drug directly to a participant's home.

Quotes about PREVENTABLE
Research Sponsor

The National Institute on Aging ( is an institute of the NIH, a U.S. Federal Government agency that provides accurate, up-to-date information about aspects of aging research, information about clinical trials, educational materials and resources about aging for the general public, and information for researchers and health professionals.